The Sharks maintained a two-point lead over Chicago for the best record in the NHL.
Nabokov won for the 29th time this season, making 26 saves and allowing only a score by Matt Beleskey 1:15 into the third period.
That goal brought the Ducks within one and it stayed a 2-1 contest until Patrick Marleau scored into an empty net with 5 seconds to play. It was Marleau's 35th goal of the season.
San Jose, which opened a five-game homestand, got first-period goals from Marc-Edouard Vlasic and Rob Blake.
Jonas Hiller gave up two goals on 24 shots to take the loss. Anaheim played the first of six straight road games.
Copyright 2010 by United Press International.
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